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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TJP1 All Species: 18.18
Human Site: T589 Identified Species: 50
UniProt: Q07157 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q07157 NP_003248.3 1748 195459 T589 Q L A S V Q Y T L P K T A G G
Chimpanzee Pan troglodytes XP_001163120 1748 195467 T589 Q L A S V Q Y T L P K T A G G
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_855568 1757 196435 T576 Q L A S V Q Y T L P K T A G G
Cat Felis silvestris
Mouse Mus musculus P39447 1745 194693 T589 Q L A S V Q Y T L P K T A G G
Rat Rattus norvegicus NP_001099736 1733 194012 T577 Q L A S V Q Y T L P K T A G G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509542 1640 183791 P518 E R N E K Q A P S L P E P K P
Chicken Gallus gallus XP_413773 1687 189478 W556 Y N G K L G S W L A I R I G K
Frog Xenopus laevis NP_001079562 1010 112460
Zebra Danio Brachydanio rerio XP_001922690 1544 172151 K422 S I L R P S M K L V K F K K G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.9 N.A. 93 N.A. 90.5 90.3 N.A. 70.4 79.2 20.1 65.2 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.9 N.A. 95.1 N.A. 93.9 93.4 N.A. 75.8 85.5 34.3 73.8 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 N.A. 100 N.A. 100 100 N.A. 6.6 13.3 0 20 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. 13.3 20 0 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 56 0 0 0 12 0 0 12 0 0 56 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 12 0 0 12 0 0 0 0 0 0 0 12 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 12 0 0 0 % F
% Gly: 0 0 12 0 0 12 0 0 0 0 0 0 0 67 67 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 12 0 0 0 0 0 0 0 0 12 0 12 0 0 % I
% Lys: 0 0 0 12 12 0 0 12 0 0 67 0 12 23 12 % K
% Leu: 0 56 12 0 12 0 0 0 78 12 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 12 0 0 0 0 0 0 0 0 % M
% Asn: 0 12 12 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 12 0 0 12 0 56 12 0 12 0 12 % P
% Gln: 56 0 0 0 0 67 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 12 0 12 0 0 0 0 0 0 0 12 0 0 0 % R
% Ser: 12 0 0 56 0 12 12 0 12 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 56 0 0 0 56 0 0 0 % T
% Val: 0 0 0 0 56 0 0 0 0 12 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 12 0 0 0 0 0 0 0 % W
% Tyr: 12 0 0 0 0 0 56 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _